Research Fellow at Newcastle University Centre for Cancer. Interests: stem cell models, prostate cancer biology, organogenesis and genome editing. š¬
Work
Newcastle University
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Prostate Cancer UK Fellow
United Kingdom of Great Britain and Northern Ireland
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Publications
ST3 beta-galactoside alpha-2,3-sialyltransferase 1 (ST3Gal1) synthesis of Siglec ligands mediates anti-tumour immunity in prostate cancer.
journal-article
ST3 beta-galactoside alpha-2,3-sialyltransferase 1 (ST3Gal1) synthesis of Siglec ligands mediates anti-tumour immunity in prostate cancer
Communications Biology
journal-article
Engineering prostate cancer in vitro: what does it take?
Oncogene
journal-article
Human prostate organoid generation and the identification of prostate development drivers using inductive rodent tissues
Development
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ST6GAL1āmediated aberrant sialylation promotes prostate cancer progression
The Journal of Pathology
journal-article
Activation of autophagy reverses progressive and deleterious protein aggregation in PRPF31 patientāinduced pluripotent stem cellāderived retinal pigment epithelium cells
Clinical and Translational Medicine
journal-article
A Review of Prostate Organogenesis and a Role for iPSC-Derived Prostate Organoids to Study Prostate Development and Disease
International Journal of Molecular Sciences
journal-article
Modified CRISPR/Cas9 mediated generation of two MKK7 knockout human embryonic stem cell lines.
Stem cell research
journal-article
A Review of Prostate Organogenesis and a Role for iPSC-Derived Prostate Organoids to Study Prostate Development and Disease
International Journal of Molecular Sciences
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Engineering Prostate Cancer from Induced Pluripotent Stem CellsāNew Opportunities to Develop Preclinical Tools in Prostate and Prostate Cancer Studies
International Journal of Molecular Sciences
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Propagation of human prostate tissue from induced pluripotent stem cells
Molecular Therapy - Methods & Clinical Development
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Disrupted alternative splicing for genes implicated in splicing and ciliogenesis causes PRPF31 retinitis pigmentosa
Nature Communications
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Human iPSC disease modelling reveals functional and structural defects in retinal pigment epithelial cells harbouring the m.3243Aā>āG mitochondrial DNA mutation
Scientific Reports
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An Induced Pluripotent Stem Cell Patient Specific Model of Complement Factor H (Y402H) Polymorphism Displays Characteristic Features of Age-Related Macular Degeneration and Indicates a Beneficial Role for UV Light Exposure
STEM CELLS
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CDK1 plays an important role in the maintenance of pluripotency and genomic stability in human pluripotent stem cells
Cell Death & Disease
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An X-chromosome pentaplex in two linkage groups: Haplotype data in Alagoas and Rio de Janeiro populations from Brazil
Forensic Science International: Genetics
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Mitochondrial DNA Control Region Polymorphism in the Population of Alagoas State, North-Eastern Brazil